If you take the time to be careful and install everything correctly it will seriously pay off. Fatal crashes may occur, missing textures, missing meshes, errors etc. A lack of patience and not carefully installing every mod can be costly. Then all your floors, or mods, are held up by duct tape and gorilla glue much like Skyrim modding except a thousand times more finicky due to the age of the engine. A modded Fallout: New Vegas is like a tower starting with the base, obviously. This is a complete and thorough guide on how to properly your mod your Fallout: New Vegas, including how to install an ENB. If you have any suggestions, please let us know. We are browsing and trying new mods quite often.
This guide is on-going, supported and updated on a regular basis by both creators.